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CaRE2 Health Equity Center Developmental Research Projects Award Application

Project Title

PI/PD Information

Name

Academic Rank

Department

Institution

email

CaRE2 member? (yes/no/submitted)

Early-Stage Investigator? (yes/no)

Other Key Personnel (1)

Name

Academic Rank

Department

Institution

email

CaRE2 member? (yes/no/submitted)

Early-Stage Investigator? (yes/no)

Other Key Personnel (2)

Name

Academic Rank

Department

Institution

email

CaRE2 member? (yes/no/submitted)

Early-Stage Investigator? (yes/no)

Please list any additional key personnel

Which CaRE2 Cores Will Be Utilized?

Tissue Modeling Core
Bioinformatics Core
Community Outreach Core

Will this proposal include CaRE2 Trainees or ESIs?

Yes
No

If yes, provide name/s and designation (undergraduate, post-bac, graduate, postdoc, ESI)

Which of ongoing CaRE2 projects will this proposal augment or collaborate with?

Full Project 1: Disparities in Mitochondrial Peptidomics and Transcriptomics in Prostate Cancer
Full Project 2: Enhancing Efficacy of Gemcitabine Nanoparticles in Pancreatic PDX Models
Pilot Project 1: Contributions of racial disparity towards the early development of pancreatic cancer
Pilot Project 2: Characterizing DNA methylation signatures in prostate tumors to understand health disparities in Black and White men
Pilot Project 3: An Organoid System Tailored to Studying Lung Cancer in Black Subjects
Pilot Project 4: Target pancreatic cancer mitochondrial redox to enhance chemotherapy efficacy in Blacks
None

What is the status of IRB approval for your proposal?

Protocol approved
Protocol approved but will need amendment
No protocol submitted yet
IRB approval is not required, this is not human subject’s research

How much funding are you requesting?

Budget Justification (Describe how the funds will be used)

What is the plan for utilizing data for submission of a peer-review grant application (or future CaRE2 full or pilot project if focusing on prostate, pancreas or lung in partnership with existing project teams)

Proposal: Please upload a 1-page document including the following sections: A) Specific Aims B) Significance and relevance to CaRE2 mission C) Study Design and Approach (including statistical considerations when appropriate) D) Timeline, benchmarks and expected outcomes

Please upload all key personnel NIH Biosketches as one pdf file

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